The first permutation of the Orion Project, the predecessor to the future Spartan programs in the 26th century, was initiated on April 13th, 2321, consisting of five test candidates.

In 2491, the Office of Naval Intelligence re-instituted the Orion Project, an attempt to create engineered super-soldiers to boost combat effectiveness.

The Battle of Installation 04 was an engagement between the UNSC Pillar of Autumn and the Covenant Fleet of Particular Justice on and around the Forerunner megastructure known as Installation 04, or Alpha Halo, in the Soell system.

The Battle for Earth was a large-scale space, air, and ground battle between the invading Covenant forces and the UNSC Home Fleet on and around Earth at the end of 2552.

The Great Schism was a conflict between the forces loyal to the Covenant, led mostly by the Jiralhanae, and the Sangheili, beginning on November 3rd, 2552 and continuing off and on until the Rule of the Created in 2558.

The Battle of Installation 00 was a major conflict between the forces stationed aboard the UNSC Forward Unto Dawn and Arbiter Thel 'Vadam's Fleet of Retribution, and the Covenant fleet loyal to the Prophet of Truth.

The Requiem Campaign was a UNSC mission to return to Requiem, and take control of the shield world away from Jul 'Mdama and his Covenant remnants in February 2558, six months after the Battle of Requiem.

The Battle of Kamchatka was a battle between Covenant remnant forces under the leadership of Jul 'Mdama, local Promethean forces under control of Cortana, and the UNSC in the form of Spartan-IV Fireteam Osiris on the planet of Kamchatka in October 2558.