A partial Orion Project candidate medical record, c. 2491. (Halo: Reach/Dr. Halsey's Journal)
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The first permutation of the Orion Project, the predecessor to the future Spartan programs in the 26th century, was initiated on April 13th, 2321, consisting of five test candidates. Though the project showed some promise, it was eventually cancelled, and all five candidates died within one year of the end of the program.
Related Media
These events are referenced in multiple reference books, including the Halo Encyclopedia, Halo Mythos, and the Halo: Official Spartan Field Manual.